DENEYSEL HEMORAJ�K �OK MODEL�NDE HAC�M KONTROLL� PRAT�K B�R KANATMA Y�NTEM�

G�ven, Hakan; H�kelek, Murat

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DENEYSEL HEMORAJ�K �OK MODEL�NDE HAC�M KONTROLL� PRAT�K B�R KANATMA Y�NTEM� [Ulus Travma Acil Cerrahi Derg]

Ulus Travma Acil Cerrahi Derg. 2003; 9(2): 102-103

DENEYSEL HEMORAJ�K �OK MODEL�NDE HAC�M KONTROLL� PRAT�K B�R KANATMA Y�NTEM�

Hakan G�ven¹, Murat H�kelek²
¹Ondokuz May�s �niversitesi T�p Fak�ltesi �lk ve Acil Yard�m Anabilim Dal�, Samsun, Turkey, [email protected]
²Ondokuz May�s �niversitesi T�p Fak�ltesi, T�bbi ve Cerrahi Ara�t�rma Laboratuvar�, Samsun, Turkey

A PRACTICAL VOLUME CONTROLLED BLEEDING METHOD IN ANIMAL HEMORHAGIC SHOCK MODEL

The bleeding method is the most widely used technique in volume controlled hemorrhagic shock model that was described as withdrawing blood by an heparinized syringe from veins of laboratory animals. However the difficulty in establishing a constant bleeding rate and volume at a desired time is the major disadvantage of this technique. This disadvantage may also lead to the mortality during the exsanguinating phase due to inconstant bleeding rate. Reversely connected infusion pump that was described in this report is a useful and practical method to withdraw blood with predetermined bleeding volume and rate. The described method can easily be applied to various pathophysiological and metabolic studies on acute blood loss.

Keywords: Bleeding method, hemorrhagic shock, laboratory animals

Hakan G�ven, Murat H�kelek. A PRACTICAL VOLUME CONTROLLED BLEEDING METHOD IN ANIMAL HEMORHAGIC SHOCK MODEL. Ulus Travma Acil Cerrahi Derg. 2003; 9(2): 102-103
Makale Dili: T�rk�e

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